Search Results: 1 genotypes retrieved

Data download

c.1279G>C

p.Gly427Arg
Mutation type:Point Mutation effect:Missense Nucleotide number:1279
Genome location:Exon9 Subdomain:Serine protease
Alpha missense prediction value:0.8973 Alpha missense prediction class:pathogenic
No. of patients reported: 1
Patient information: Monoallelic variation (1); Biallelic variation (0)
Patient Sex Age Genotype PC: amidolytic act (%) PC: clotting act (%) PC: Ag (%) PCD type Clinical presentation (age) First onset age Country Comments Reference
1 NA NA hetero 48 43 80 II NA NA Japan NA PMID: 7482420